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International Study Group for Systems Biology - 2010 10.09.2010

International Study Group for Systems Biology - 2010

The 14th workshop of ISGSB was held in Vladimir (Russia) from 6th to 10th of September, 2010. ICMPh was the main organizer of this meeting; and the head of  the mathematical modeling department Ya.R. Nartsissov was its chairman. "Modern Trends in System Biology. Virtual modeling and Regulation" became a main topic of the workshop.
There were nine different themes of presentations:
  • Fundamental problems of System Biology;
  • Regulation and control in metabolic networks;
  • System Biology and regulatory aspects of gene expression;
  • Virtual modeling of living systems;
  • Modeling of glycolysis and its regulation;
  • Receptors and transporters of neurotransmitters. Modeling and application;
  • Experimental model as a tool for research in system biology;
  • Application of system biology approach to description of ATP synthesis and anabolic processes.

Presentations which were done by the staff of ICMPh:

within the "Virtual modeling of living systems":

    • Ya. R. Nartsissov                
      Spatial-time gradients and their modeling in virtual phantoms. 

within the "Receptors and transporters of neurotransmitters. Modeling and application.":  

    • S. E. Boronovsky and Ya. R. Nartsissov                
      Probability simulator of enzyme activity and its application to description of transmembrane currents through glycine receptor.  
    • Kofanova Olga, Boronovsky Stanislav, Mashkovtseva Elena, Nartsissov Yaroslav                
      Computer simulation of glutamate transport via EAAT 4 neuron transporter.  
    • Zaytsev Kirill, Boronovsky Stanislav, Mashkovtseva Elena, Nartsissov Yaroslav                
      Computer simulation of glycine transport in mammalian neurons. 

within the "Experimental model as a tool for research in system biology":

    • Elena V. Sheshegova, Ekaterina S. Tyukina, Yaroslav R. Nartsissov                
      Effect of glycine on pial brain vessels vasodilatation. 
    • Selin Alexey A., Lobysheva Natalia V., Nartsissov Yaroslav R., Yaguzhinsky Lev S.                
      Mitochondria as therapeutic target of glycine in the model of ischemic stroke in vitro. 

within the "Application of system biology approach to description of ATP synthesis and anabolic processes":

    • Mashkovtseva E.V., Boronovsky S.E., Nartsissov Ya.R.                
      Mechano-probability Model of FoF1-ATPsynthase Catalytic Cycle: A Novel Approach to ATP Synthesis and Hydrolysis Description 

Abstracts were published together with other  workshop materials.


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